Published: 20 July, 2021 | Volume 5 - Issue 1 | Pages: 027-041
Figure 8:
Coronavirus S protein-mediated membrane fusion- model. A hypothetical depiction of the native prefusion S- protein (left) is depicted binding to cellular CEACAM- receptors. S1 subunit dissociation and S2 unfolding generates pre hairpin- structures (middle) depicted with cell membrane-intercalated FPs and exposed heptad repeat regions (HR1 and -2). Prehairpin closure through a lipid stalk intermediate generates a highly -stable, rodlike 6-HB, in which HR2- helices are positioned antiparallel to an interior HR1 trimer. Palmitates are shown extending from endo-domain- cysteines (C).
Read Full Article HTML DOI: 10.29328/journal.apb.1001014 Cite this Article Read Full Article PDF
HSPI: We're glad you're here. Please click "create a new Query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."