Figure 21

The importance of gestational age in first trimester, maternal urine MALDI-Tof MS screening tests for Down Syndrome

Ray K Iles*, Nicolaides K, Pais RJ, Zmuidinaite R, Keshavarz S, Poon LCY and Butler SA

Published: 31 December, 2019 | Volume 3 - Issue 1 | Pages: 010-017

apb-aid1008-g0021

Figure 21:

Mass bins that compose the 19 bins, 9 bins, 7 bins and 2 Bins algorithms for predicting Downs/T21 pregnancy based on MALDI-ToF mass spectral measurement (Panel A). Estimated optimal cut-offs for all algorithms and its computed sensitivity and false positive rate (1-specificity). ROC plot of predictive algorithms for Downs/T21 pregnancy considering all data with gestational age ranging from 11 to 14 weeks (Panel B). ROC plots of predictive algorithms only considering data with a particular gestational age, either 12 weeks or 13 weeks of gestation (Panel C and D, respectivelly).

Read Full Article HTML DOI: 10.29328/journal.apb.1001008 Cite this Article Read Full Article PDF

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