Research Article
Published: 03 July, 2020 | Volume 4 - Issue 1 | Pages: 012-014
The novel coronavirus 2019-nCoV has become a bane to mankind and spread worldwide and infected many people. Thus, there is an urgent need of a cure for the severe pneumonia disease caused by this virus. In this study, In silico comparative analysis has been done for HIV protease inhibitors on coronavirus 3CLpro protein which has shown the major interactions and common amino acid residues involved in interactions. The amino acid interaction analysis has revealed two amino acids ARG4, LYS5 to be the major amino acids targets among selected ligands. The binding energy analysis has also revealed Cobicistat as one of these best suited ligand for 3CLpro.
Read Full Article HTML DOI: 10.29328/journal.apb.1001011 Cite this Article Read Full Article PDF
2019-nCoV; Protease inhibitors; Pneumonia; 3CLpro; Interaction analysis; Ligands
HSPI: We're glad you're here. Please click "create a new Query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."